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Severe early-onset obesity-insulin resistance syndrome due to SH2B1 deficiency
1 associated gene
No signs/symptoms info
PROTEIN INTERACTIONS: 1
Pilocytic astrocytoma
7 associated genes
No signs/symptoms info
Severe early-onset obesity-insulin resistance syndrome due to SH2B1 deficiency
Pilocytic astrocytoma

SH2B1
(UniProt - OMIM)
 BRAF
(UniProt - OMIM)
FGFR1
(UniProt - OMIM)
KIAA1549
(UniProt - OMIM)
KRAS
(UniProt - OMIM)
NTRK2
(UniProt - OMIM)
RAF1
(UniProt - OMIM)
SRGAP3
(UniProt - OMIM)

INTERACTOME
ASSOCIATIONS
(click on a score value to see the evidence)
SH2B1
(0.75)
NTRK2


Citations in the biomedical literature:


Severe early-onset obesity-insulin resistance syndrome due to SH2B1 deficiency
SH2B1
Pilocytic astrocytoma
BRAF FGFR1 KIAA1549 KRAS NTRK2 RAF1
SRGAP3



Severe early-onset obesity-insulin resistance syndrome due to SH2B1 deficiency
Pilocytic astrocytoma

Classification (Orphanet):
- Rare endocrine disease
- Rare genetic disease
Classification (Orphanet):
(no data available)
Classification (ICD10):
- Endocrine, nutritional and metabolic diseases -
Classification (ICD10):
(no data available)
Epidemiological data:
Class of prevalence: <1 / 1 000 000
Average age onset: childhood
Average age of death: -
Type of inheritance: autosomal dominant
Epidemiological data:
Class of prevalence: -
Average age onset: variable
Average age of death: -
Type of inheritance: sporadic
External references:
No OMIM references
No MeSH references
External references:
No OMIM references
No MeSH references
No signs/symptoms info available.